Soft Matter published our article (2025): Ravid et al.: Coupling Anisotropic Curvature and Nematic Order: Mechanisms of Membrane Shape Remodeling.
In the article we studied theoretically how anisotropic curved membrane components (CMCs), i.e. curved nanodomains, control vesicle morphology through curvature sensing,
nematic alignment, orientational ordering, topological defects and volume constraints (the concept introduced by our collaborator Veronika Kralj-Iglič in 1990s). By comparing arc-shaped and saddle-shaped CMCs, we identify a rich phase diagram of vesicle shapes.
For fully CMC-covered vesicles, arc-shaped CMCs drive a pearling-to-cylinder transition as nematic interactions strengthen, while on partially CMC-covered vesicles the saddle-shaped
CMCs stabilize necks between two convex membrane regions without CMCs. By investigating the in-plane nematic field, we find that topological defects consistently localize to high-curvature regions,
revealing how intrinsic and deviatoric curvature effects cooperate in membrane remodeling. These findings establish a unified framework for understanding how proteins and lipid
(nano)domains with anisotropic intrinsic curvature shape cellular structures—from organelle morphogenesis to global cell shape.
Link,
PDF.
Reduced volume-binding strength plane for arc-shaped CMCs. The CMC and bare regions of the membrane are shown in blue and gray, respectively.
Koncert naše umetniške sodelavke Lare Oprešnik 31. 8. 2025 v Radovljici (Baročna dvorana Radovljiške graščine).
Spletna stran,
program, novice FE UL.
Glejte še Novice FE UL o nedavni publikaciji skladbe "Fuga" naše umetniške sodelavke, pianistke in skladateljice Lare Oprešnik
Spletna stran.
Izšel je zbornik 13. Sokratskih predavanj (Proceedings of 13th Socratic Lectures 2025):
link.
Naša sodelavka prof. dr. Veronika Kralj-Iglič (tudi sourednica zbornika) je napisala refleksijo na vse umetniške dogodke v zvezi s Sokratskimi predavanjimi in VIP pripravljalnim STEAM projektom "Nanostrukturomom" ((št. projekta 802-12/2024-5)) pod naslovom:
"Z-STEAM activities at 13th Socratic Lectures Symposium, Concert at City Hall and Opera Coronation of Poppaea". Glejte:
Spletna stran,
ali pripeti PDF.
The Laboratory of Clinical Biophysics, Faculty of Health Sciences and Laboratory of Physics, Faculty of Electrical Engineering, University of Ljubljana, organise in Ljubljana the "European Joint Theory/Experiment Meeting on Membranes" (EJTEMM 2026) from 28th to 30th of January 2026:
Link.
V okviru pripravljalnega VIP STEAM projekta "Nanostrukturom" in 13. Sokratskih predavanj: povezava je v nedeljo
8. junija 2025 Lab. za klinično biofiziko ZF UL in Lab. za fiziko FE organiziral koncert na Akademiji za glasbo (AG) UL: povezava.
Na koncertu je sodelavka AG UL in LF FE UL, pianistka in skladateljica Lara Oprešnik, predstavila svojo novo skladbo z naslovom E=mc2. Program koncerta,
opis skladbe E=mc2.
Izšel je zbornik 12. Sokratskih predavanj in posnetek spremljajočega koncerta
Povezava do novice.
Aleš Iglič was awarded a Certificate of Recognition by the American Physical Society for being an Outstanding Referee for the Physical Review Journals
Certificate.
Revija Proceedings of the National Academy of Sciences (PNAS) (IF=11.2) je objavila članek: R. K. Sadhu, M. Luciano, W. Xi, C. Martinez-Torres, M. Schröder, C. Blum, M. Tarantola, S. Villa, S. Penič, A. Iglič, C. Beta,
O. Steinbock, E. Bodenschatz, B. Ladoux, S. Gabriele, Nir S. Gov: A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge. PNAS, 121 (12): e2306818121, 2024. DOI: 10.1073/pnas.2306818121,
spletna stran, prispevek v Delu, link na predavanje na CNR_IBBR Napoli pri katerem sta sodelovala tudi dva člana našega laboratorija.
Revija ACS Applied Materials & Interfaces (IF=9.5) je objavila članek: Nanoscale topography of anodic TiO2 nanostructures is crucial for cell-surface interactions, ACS Applied Materials & Interfaces,
16 (4): 4430–4438, 2024, pri katerem sta z elektrostatskimi izračuni (Figs. 6, 7) sodelovala tudi dva člana našega laboratorija.
PDF in spletna stran.
Tednik REPORTER je dne 11. septembra 2023 objavil članek o naši sodelavki prof. dr. Veroniki Kralj-Iglič in njeni družini
PDF članka.
Prestižna revija Nature Communications je objavila članek z naslovom “Experimental and theoretical model for the origin of coiling of cellular protrusions around fibers” (Nat. Commun. vol. 14: 5612, 2023) pri katerem sta sodelovala člana Fakultete za
elektrotehniko doc. dr. Samo Penič in prof. dr. Aleš Iglič.
Povezava do novice.
Prispevek v Delu.
Prestižna revija Advanced Materials (IF=32) je objavila članek z naslovom "Curvature in Biological Systems:
Its Quantification, Emergence, and Implications across the Scales" (Adv. Mater. 35: 2206110, 2023) pri katerem
je sodeloval član našega laboratorija prof. Aleš Iglič. Povezava do članka.
Povezava do spletne strani.
Član Laboratorija za fiziko Dr. Szymon Starzonek je kot vodilni avtor objavil članek z naslovom "New scaling paradigm for dynamics in glass-forming systems" v reviji Progress in Materials Science, ki ima faktor vpliva 48.165. Povezava do novice.
Objavljena je bila kritika knjige Poklon življenjski radosti, Ob 100-letnici rojstva Nika Kralja, čanice našega laboratorija prof. dr. Veronike Kralj-Iglič. Povezava do kritike.
Science meets music: a composition for the 45th FEBS Congress. In the following Q and A, Veronika Kralj-Iglič tells us how science and music overlap in her life, and explains the background to the composition. Link to site and video
R. K. Kumar Sadhu, C. Hernandez-Padilla, Y.E. Eisenbach, S. Penič, L. Zhang, H.D. Vishwasrao, B. Behkam, K. Konstantopoulos, H. Shroff, A. Iglič, E. Peles, A. S. Nain, N. S. Gov:
Experimental and theoretical model for the origin of coiling of cellular protrusions around fibers.Nature Communications 14: 5612, 2023.
L. Mesarec, W. Góźdź, V. Kralj-Iglič, S. Kralj, A. Iglič:
Coupling of nematic in-plane orientational ordering and equilibrium shapes of closed flexible nematic shells.Scientific Reports 13:10663, 2023.
Ž. Pandur, S. Penič, A. Iglič, V. Kralj-Iglič, D. Stopar, M. Drab:
Surfactin molecules with a cone-like structure promote the formation of membrane domains with negative spontaneous curvature and induce membrane invaginations.Journal of Colloid and Interface Science, 650(B): 1193-1200, 2023.
R. Kumar Sadhu, S. R. Barger, S. Penič, A. Iglič, M. Krendel, N.C. Gauthiere, N.S. Gov:
A theoretical model of efficient phagocytosis driven by curved membrane proteins and active cytoskeleton forces.Soft Matter 19, 31-43, 2023.
V. Kralj-Iglič, G. Pocsfalvi, L. Mesarec, V. Šuštar, H. Hagerstrand, A. Iglič:
Minimizing isotropic and deviatoric membrane energy – an unifying formation mechanism of different cellular membrane nanovesicle types.PLOS ONE: 15(12): e0244796, 2021. DOI: 10.1371/journal.pone.0244796.
B.R. Graziano, J. P. Town, E. Sitarska, T. L. Nagy, M. FoÂnarič, S. Penič, A. Iglič, V. Kralj-Iglič, N.S. Gov, A. Diz-Munoz, O.D. Weiner:
Cell confinement reveals a branched-actin independent circuit for neutrophil polarity,
PLOS Biol., 17(10): e3000457, 2019.
A.V. Dubtsov, S.V. Pasechnik, D.V. Shmeliova, A.Sh. Saidgaziev, E. Gongadze, A. Iglič, S. Kralj:
Liquid Crystalline Droplets in Aqueous Environment: Electrostatic Effects,
Soft Matter, 14(47): 9619-9630, 2018.
R. Imani, R. Dillert, D.W. Bahnemann, M. Pazoki, T. Apih, V. Kononenko, N. Repar, V. Kralj-Iglič, G. Boschloo, D. Drobne, T. Edvinsson, A. Iglič: Multi functional Gadolinium-Doped Mesoporous TiO2 Microbeads: A potential for cancer diagnosis and treatment, Small, 1700349, 2017.
M. Kulkarni, A. Mazare, J. Park, E. Gongadze, M.S. Killian, S. Kralj, K. von der Marke, A. Iglič, P. Schmuki: Protein interactions with layers of TiO2 nanotube and nanopore arrays: morphology and surface charge influence, Acta Biomaterialia, 45: 357Â366, 2016.
M. Kulkarni, Y. Patil-Sen, I. Junkar, C. V. Kulkarni, M. Lorenzetti, A. Iglič: Wettability studies of topologically distinct titanium surfaces, Coll. Surf. B: Biointerfaces, 129: 47Â53, 2015.
E. Gongadze, A. Iglič: Asymmetric size of ions and orientational ordering of water dipoles in electric double layer model in an analytical mean-field approach, Electrochim. Acta, 178: 541Â545, 2015.
Perutkova Š., Daniel M., Rappolt M., Pabst G., Dolinar G.,Kralj-Iglič V., Iglič A.: Elastic deformations in hexagonal phases studied by small angle X-ray diffractionand simulations, Phys. Chem. Chem. Phys., 13: 3100Â3107, 2011.
Gongadze E., Kabaso D., Bauer S., Slivnik T., Schmuki P., van Rienen U., Iglič A.: Adhesion of osteoblasts to a nanorough titanium implant surface, Int. J. Nanomed., 6: 1801-1816, 2011.
Veranič P., Lokar M., Schuetz G.J., Weghuber J., Wieser S., Hagerstrand H., Kralj-Iglič V., Iglič.: Different types of cell-to-cell connections mediated by nanotubular structures,
Biophys J., 95: 4416-4425, 2008.
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